Can fibroadenomas grow quickly?
In addition to simple fibroadenomas, there are: Complex fibroadenomas. These can contain changes, such as an overgrowth of cells (hyperplasia) that can grow rapidly. A pathologist makes the diagnosis of a complex fibroadenoma after reviewing the tissue from a biopsy.
What percentage of phyllodes tumors are malignant?
Reports have suggested, however, that about 85-90% of phyllodes tumors are benign and that approximately 10-15% are malignant. Although benign phyllodes tumors do not metastasize, they have a tendency to grow aggressively and can recur locally. Like other sarcomas, malignant phyllodes tumors metastasize hematogenously.
Can a phyllodes tumor spread?
Phyllodes tumors tend to grow quickly, but they rarely spread outside the breast. Although most phyllodes tumors are benign (not cancerous), some are malignant (cancerous) and some are borderline (in between noncancerous and cancerous).
Do phyllodes tumors stop growing?
Outlook for Phyllodes Tumors
Your outlook is excellent if you had a benign tumor removed with surgery. Treatment often cures malignant phyllodes tumors, but they’re more likely to grow back. They can spread beyond your breast to your lungs.
Can a borderline phyllodes tumor become malignant?
Phyllodes (fil-oy-deez) tumors are a rare form of breast tumor; they can be benign (not cancerous), malignant (cancerous), or borderline (having characteristics of both).
What are the chances of phyllodes tumor recurrence?
Background: Phyllodes tumours (PT) of the breast are fibro-epithelial neoplasms that are known to recur locally in up to 19% of patients. The failure to achieve adequate surgical margins is an important risk factor for local recurrence.
Are phyllodes tumors curable?
Whether phyllodes tumors are benign, borderline, or malignant, the treatment is the same: surgery to remove the tumor, along with at least 1 centimeter of surrounding healthy breast tissue. Some doctors feel that an even wider margin of healthy tissue should be removed.
Can a benign phyllodes tumor become malignant?
Most phyllodes tumors are benign, but in rare cases they can be malignant (cancerous). In addition, their behavior is unpredictable. In rare cases, a benign tumor can recur (grow back) as a cancer.
What are the signs of phyllodes tumor?
The most common symptom of a phyllodes tumor is a breast lump that you or your doctor can feel while examining the breasts. Phyllodes tumors tend to grow quickly, within a period of weeks or months, to a size of 2-3 cm or sometimes larger.
Can phyllodes tumor be misdiagnosed?
It has been suggested that phyllodes tumors may be misdiagnosed as fibroadenomas by core biopsy. However, in this case, pathology supports correct initial diagnosis of fibroadenoma and demonstrates a portion of the original fibroadenoma along the periphery of the malignant phyllodes tumor.
What does low grade phyllodes tumor mean?
AFIP defines low-grade phyllodes tumors as fibroepithelial neoplasms with well-defined borders, uniform leaf-like processes, rare to moderate mitoses (<3 mitoses per 10 high-power fields), mildly increased cellularity often with subepithelial accentuation, no to mild cytological atypia and no sarcomatous stromal …
What is the difference between fibroadenoma and phyllodes tumor?
Fibroadenomas grow up to 2-3 cm and then stop growing but phyllodes tumors grow continually and sometimes are to 40 cm big. Both these lesions have two components, epithelial and stromal. Clinically fibroadenomas are well circumscibed, hard, oval, movable lesions.