Best answer: Is Stage 4 HER2 positive breast cancer curable?

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What is the life expectancy of HER2-positive metastatic breast cancer?

With a median follow-up of 48 months, median OS and PFS were 63 months (CI95%, 50-71), and 18 months (CI95%, 15-21) respectively. In 111 patients (26.3%) classified as LTR, median OS was 110 months (CI95%, 95-not reached) versus 56 months in non-LTR patients (CI95%, 47-68).

What is the longest someone has lived with Stage 4 breast cancer?

Stage 4: Kim Green Has Lived With Metastatic Breast Cancer For Past 19 Years. Kim Green defies the odds for those living with incurable metastatic breast cancer. Her mother died of metastatic breast cancer at 37, but Green has been living with it for 19 years.

What is the survival rate of HER2-positive cancer?

The 4-year survival rates are as follows: HR+/HER2-: 92.5% HR+/HER2+: 90.3% HR-/HER2+: 82.7%

Is Stage 4 breast cancer a death sentence?

Stage 4 cancer, also known as metastatic cancer, is the most advanced stage. It is the least likely to be cured and is unlikely to end up in remission. That doesn’t mean it’s automatically a death sentence—many stage 4 cancer patients live for many years—but the prognosis is not likely to be good.

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Is HER2-positive a death sentence?

Current treatment algorithms for invasive HER2-positive disease has transformed the face of a disease with a death sentence to one with prolonged and overall survival benefit.

Is chemo necessary for HER2-positive?

Trastuzumab and chemotherapy are even recommended for women with very small, HER2-positive breast cancers. Tumors as small as 0.5 cm often warrant such treatment. However, decisions must be individualized based on your own individual risk.

What is the most aggressive form of breast cancer?

Triple-negative breast cancer (TNBC) is considered an aggressive cancer because it grows quickly, is more likely to have spread at the time it’s found and is more likely to come back after treatment than other types of breast cancer.

What is the longest time someone has lived with metastatic breast cancer?

She survived for 18 years after the diagnosis of metastatic breast cancer (MBC) while maintaining a good quality of life. To the authors’ knowledge, this is the first reported case in the literature with the longest overall survival in a patient with MBC.

What is the longest a person has lived with MBC?

Rita Arditti: Lived over 30 years with MBC.

Is HER2-positive cancer aggressive?

In about 1 of every 5 breast cancers, the cancer cells have extra copies of the gene that makes the HER2 protein. HER2 -positive breast cancers tend to be more aggressive than other types of breast cancer.

Can cancer come back while on Herceptin?

None of the women were treated with Herceptin. The researchers found: 10% to 23% of women diagnosed with small, HER2-positive cancer had a recurrence within 5 years of diagnosis compared to about 5% of women diagnosed with HER2-negative cancer.

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What’s the worst stage of cancer?

When you’re diagnosed with cancer, your doctor will tell you what stage it is. That will describe the size of the cancer and how far it’s spread. Cancer is typically labeled in stages from I to IV, with IV being the most serious.

How long can you live when breast cancer spreads to the brain?

Prognosis. Development of brain metastases in breast cancer has a poor overall prognosis, with a median survival between 2 and 27 months without treatment.

How long can you live when cancer spreads to bones?

The authors note that most people live for 12–33 months after a diagnosis of metastatic cancer in the bones.