Can ductal carcinoma in situ spread?

How quickly does DCIS spread?

Grade 1 DCIS is almost always ER and PR positive and is a very slow growing form of cancer. It can take years, even decades, to see progression of the disease. In some cases, it may take such a long time to spread beyond the breast duct that it is not an event that will happen during a person’s lifetime.

What percentage of DCIS will become invasive?

“DCIS is non-invasive so women do not die of it. Their real concern arises if they develop invasive cancer and the cancer spreads. ” According to the study, the group of patients with the lowest risk has only a 2 percent chance of developing invasive cancer at 5 years and a 4 percent chance at 8 years.

Should I have a mastectomy for DCIS?

If the DCIS is large, a mastectomy may be recommended. Removing the opposite breast usually isn’t recommended; chemotherapy usually isn’t recommended either. Hormonal therapy may be recommended if the DCIS is hormone-receptor-positive. DCIS is NOT invasive cancer.

What are the chances of DCIS coming back?

When you have had DCIS, you are at higher risk for the cancer coming back or for developing a new breast cancer than a person who has never had breast cancer before. Most recurrences happen within the 5 to 10 years after initial diagnosis. The chances of a recurrence are under 30%.

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Why did I get DCIS?

DCIS forms when genetic mutations occur in the DNA of breast duct cells. The genetic mutations cause the cells to appear abnormal, but the cells don’t yet have the ability to break out of the breast duct. Researchers don’t know exactly what triggers the abnormal cell growth that leads to DCIS.

Is carcinoma in situ really cancer?

In general, carcinoma in situ is the earliest form of cancer, and is considered stage 0. An example of carcinoma in situ is ductal carcinoma in situ, or DCIS, which is considered an early form of breast cancer and occurs when abnormal cells form a breast’s milk duct.

How is carcinoma in situ treated?

Treatment of DCIS has a high likelihood of success, in most instances removing the tumor and preventing any recurrence. In most people, treatment options for DCIS include: Breast-conserving surgery (lumpectomy) and radiation therapy. Breast-removing surgery (mastectomy)

Does DCIS ever go away?

Clusters of abnormal cells like D.C.I.S. can sometimes disappear, stop growing or simply remain in place and never cause a problem. The suspicion is that the abnormal cells may be harmless and may not require treatment.

What stage is high grade DCIS?

DCIS that is high grade, is nuclear grade 3, or has a high mitotic rate is more likely to come back (recur) after it is removed with surgery. DCIS that is low grade, is nuclear grade 1, or has a low mitotic rate is less likely to come back after surgery.

What are the chances of high grade DCIS returning?

Results of a number of small studies (16-18,25,29,31-40) suggest that women whose initial DCIS lesions have comedo necrosis or high nuclear grade have a high recurrence rate (13%–38%) over 5–10 years, whereas women with low-nuclear-grade DCIS lesions or lesions without comedo necrosis have a low recurrence rate (5%–7%) …

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