What type of drug is filgrastim?
Filgrastim is in a class of medications called colony-stimulating factors. It works by helping the body make more neutrophils.
Why is filgrastim given 24 hours after chemotherapy?
This medication is usually given at least 24 hours after chemotherapy to stimulate the growth of new, healthy, white blood cells (WBC). Pegfilgrastim is a longer acting form of filgrastim and the manufacturer recommends that it should not be given within 14 days prior to chemotherapy.
Is Tbo filgrastim chemotherapy?
Tbo-filgrastim (Granix), manufactured by Teva, is a recombinant human granulocyte colony-stimulating factor (G-CSF) FDA approved to reduce the duration of severe neutropenia in adults with non-myeloid malignancies receiving myelosuppressive chemotherapy with significant evidence of febrile neutropenia (FN).
When should you not give filgrastim?
The manufacturer recommends that the first dose of filgrastim be given no sooner than 24 hours after chemotherapy. Your doctor will discontinue therapy with filgrastim when your white blood cell count has reached acceptable levels.
How can I increase my white blood cells after chemo?
The only treatment that has been proved to increase the number of white blood cells after chemotherapy is an injectable medicine that stimulates the bone marrow to make white blood cells faster.
How long does Neupogen stay in the body?
Neulasta is a long lasting medicine, with peak levels achieved 24 hours after injection, levels drop considerably over the first 7 days and after 14 days there is only a small amount remaining in the body.
Does Neupogen cause hair loss?
diarrhea; headache; numbness; or. rash, thinning hair.
When is the best time to inject filgrastim?
When should I administer filgrastim? The first filgrastim injection is usually given on the fourth day of your chemotherapy cycle for a total of seven days. Some chemotherapy treatments might require you to administer the filgrastim syringes on a different day.
When do you give G-CSF after chemo?
G-CSF is usually started 24 hours or more after your chemotherapy finishes. You usually have it daily. Your doctor or pharmacist will tell you how many injections you need. Some types of G-CSF stay in the body for longer.
Why do you get a shot the day after chemo?
CSFs help your body make more white blood cells. This lowers your risk for febrile neutropenia. CSFs include Neupogen (filgrastim), Neulasta (pegfilgrastim), and Leukine and Prokine (sargramostim). They are usually given as shots 24 hours after a chemotherapy treatment.
Can you take ibuprofen with filgrastim?
Bone pain is a common side effect of tbo-filgrastim. Your doctor may recommend you take acetaminophen (Tylenol), ibuprofen (Advil, Motrin) other medications to relieve pain. Take only the dosage your doctor recommends.
What is the difference between TBO-Filgrastim and filgrastim?
While there are no significant differences in the results between filgrastim and tbo-filgrastim in a clinical setting, tbo-filgrastim offers significant cost savings over filgrastim. A new hospital-wide formulary change resulted in the replacement of filgrastim with tbo-filgrastim for all on- and off-label indications.
What does Tbo-filgrastim stand for?
FDA notes that “tbo” stands for the medical abbreviation, “toluidine blue O. 2” However, it is not thought that this abbreviation would cause confusion in this context or conflict with the proper name, “tbo-filgrastim” and therefore FDA has no objection to its possible selection.