Is there a tumor marker for testicular cancer?

Tumor markers in testicular cancer diagnosis and staging

Does testicular cancer have tumor markers?

There are three important tumor markers for testicular cancer: Alpha-fetoprotein (AFP) Human chorionic gonadotropin (HCG) Lactate dehydrogenase (LDH)

Would blood test show testicular cancer?

A blood test will be performed to test for certain proteins in your blood. These proteins are called tumor markers and can be used to diagnose testicular cancer.

When do you check tumor markers after orchiectomy?

Serum tumour markers, both before, and 5-7 days after orchiectomy (AFP and hCG) and LDH. The latter is mandatory in advanced tumours.

When do you repeat testicular tumor markers?

Nadir serum tumor markers (AFP, hCG, and LDH) should be repeated at appropriate T1/2 time intervals after orchiectomy for staging and risk stratification.

How long can you have testicular cancer without knowing?

Very few men who have testicular cancer felt pain at first. Many men do not tell their health care provider about these signs. On average, men wait for about five months before saying anything. Since the tumor can spread during that time, it is vital to reach out to a urologist if you notice any of these signs.

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Is hCG a tumor marker?

Since hCG is not normally present in men or non-pregnant women, it is useful as a tumor marker. If the tumor or cancer is producing hCG, then the hCG test can be used to help detect and monitor tumor activity.

How can you tell if you got testicular cancer?

Signs and symptoms of testicular cancer include:

  • A lump or enlargement in either testicle.
  • A feeling of heaviness in the scrotum.
  • A dull ache in the abdomen or groin.
  • A sudden collection of fluid in the scrotum.
  • Pain or discomfort in a testicle or the scrotum.
  • Enlargement or tenderness of the breasts.
  • Back pain.

Is testicular cancer fast growing?

There are two main types of testicular cancer – seminomas and nonseminomas. Seminomas tend to grow and spread more slowly than nonseminomas, which are more common, accounting for roughly 60 percent of all testicular cancers. How quickly a cancer spreads will vary from patient to patient.

Which is worse seminoma or nonseminoma?

Seminomas are very sensitive to radiation therapy. Nonseminoma: This more common type of testicular cancer tends to grow more quickly than seminomas.

What is a normal tumor marker level?

Normal range: < 2.5 ng/ml. Normal range may vary somewhat depending on the brand of assay used. Levels > 10 ng/ml suggest extensive disease and levels > 20 ng/ml suggest metastatic disease.

When do you start chemo after orchiectomy?

This is a standard treatment option after orchiectomy when the serum tumor marker levels have returned to normal, none of the lymph nodes are larger than 2 cm, and there are no more than 5 enlarged lymph nodes. Chemotherapy may be recommended after RPLND if a large amount of cancer is found in the removed lymph nodes.

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Is CEA a tumor marker?

CEA is a type of tumor marker. Tumor markers are substances made by cancer cells or by normal cells in response to cancer in the body. A high level of CEA can be a sign of certain types of cancers. These include cancers of the colon and rectum, prostate, ovary, lung, thyroid, or liver.

What cancers cause high hCG?

Takeaway. Ovarian and testicular cancer can dramatically increase hCG levels. Other cancer types, such as breast and lung cancer, may also increase hCG blood levels.

What is a yolk sac tumor?

Listen to pronunciation. (yok sak TOO-mer) A rare type of cancer that begins in germ cells (cells that form sperm or eggs). Yolk sac tumors occur most often in the ovary or testicle, but they may also occur in other areas of the body, such as the chest, abdomen, or brain.