Question: Where would you expect to find germ cell tumors?

What is the most common germ cell tumor?

Teratomas are the most common type of germ cell tumor to develop in extragonadal (not in the ovary or testes) areas. Doctors usually treat teratomas with surgery because chemotherapy doesn’t work in a benign tumor.

When do germ cell tumors form?

Ovarian germ cell tumors usually develop in young women under 20, but they can grow in older women, too. Most often, a tumor only grows in one ovary. Treatment for malignant tumors includes surgery or chemotherapy.

What are the two types of germ cell tumors?

There are two types of germ cell tumors that start in the gonads, or reproductive organs: seminomas, which are slower-growing, and nonseminomas, which are faster-growing tumors. These germ cell tumors typically form during puberty.

What is the survival rate of germ cell tumor?

The 5-year survival rate for teens ages 15 to 19 is 93%. The survival and cure rates also depend on several factors, including the stage of the disease. The cure rate for children with a stage I or stage II germ cell tumor is 90%. The cure rate for a stage III tumor is 87%.

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How do you test for germ cell tumors?

In addition to a physical examination, the following tests may be used to diagnose a germ cell tumor:

  1. Biopsy. A biopsy is the removal of a small amount of tissue for examination under a microscope. …
  2. Blood tests. Alpha-fetoprotein (AFP). …
  3. Ultrasound. …
  4. Computed tomography (CT or CAT) scan. …
  5. Magnetic resonance imaging (MRI).

How common are germ cell tumors?

Germ cell tumors are rare. Germ cell tumors account for about 2 to 4 percent of all cancers in children and adolescents younger than age 20. Germ cell tumors can spread (metastasize) to other parts of the body. The most common sites for metastasis are the lungs, liver, lymph nodes, and central nervous system.

How do they treat germ cell tumors?

Treatment options for germ cell tumors may include surgery to remove the tumor, chemotherapy with drugs that kill cancer cells and radiation therapy with powerful energy beams.

What percentage of germ cell tumors are malignant?

Malignant germ cell tumors of the mediastinum are uncommon, representing only 3 to 10% of tumors originating in the mediastinum. They are much less common than germinal tumors arising in the testes, and account for only 1 to 5% of all germ cell neoplasms.

What is germ cell tumor symptoms?

Common signs of germ cell tumors include: A mass on your ovaries or testicles. Belly pain and swelling (caused by tumor) Bathroom troubles (a hard time pooping or holding in your pee, if the tumor is near your pelvis)

Where do germ cells come from?

In many animals, the germ cells originate in the primitive streak and migrate via the gut of an embryo to the developing gonads. There, they undergo meiosis, followed by cellular differentiation into mature gametes, either eggs or sperm.

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Is germ cell tumor curable?

Germ cell tumours generally respond very well to chemotherapy and most people are cured. Even cancers that have spread are still very treatable with chemotherapy.

What is the most common type of testicular tumor?

The most common type of testis cancer is a germ cell tumor. There are two main types of GCT: seminoma and nonseminomatous germ cell tumors (NSGCT). Both seminoma and NSGCT occur at about the same rate, and men can have seminoma, NSGCT or a combination of both.

Do germ cell tumors run in families?

[1] Ovarian germ cell tumors are rare malignancies. Familial clustering of testicular malignancies is well documented in literature. Children or siblings of affected family members are at higher risk for testicular germ cell tumors.