What is a normal cancer marker for pancreatic cancer?
CA 19-9: CA 19-9 is a tumor marker commonly associated with pancreatic cancer. The normal range of CA 19-9 is between 0 and 37 U/mL (units/milliliter), but people with pancreatic cancer often have higher levels.
What is considered a high CA 19-9 level?
A CA19-9 level of >100 U/mL is more likely to indicate the presence of malignant diseases, especially early stage of pancreatic cancer (1). The specificity of CA19-9 level >1,000 U/mL for pancreatic cancer was 99% (2).
What is considered a high tumor marker number?
Normal range: < 2.5 ng/ml. Normal range may vary somewhat depending on the brand of assay used. Levels > 10 ng/ml suggest extensive disease and levels > 20 ng/ml suggest metastatic disease.
How reliable is CA 19-9?
Overall, an elevated serum CA 19-9 level has a sensitivity of 79–81% and a specificity of 82–90% for diagnosing pancreatic cancer in symptomatic patients.
What are the symptoms of stage 1 pancreatic cancer?
They may include:
- Abdominal pain that radiates to your back.
- Loss of appetite or unintended weight loss.
- Yellowing of your skin and the whites of your eyes (jaundice)
- Light-colored stools.
- Dark-colored urine.
- Itchy skin.
- New diagnosis of diabetes or existing diabetes that’s becoming more difficult to control.
- Blood clots.
How reliable are tumor markers?
There has been no evidence to prove that tumor markers are 100 percent reliable for determining the presence or absence of cancer. Many circumstances, such as other health issues or disease, can contribute to raised tumor marker levels.
How long does it take to get CA 19-9 results?
However, CA 19-9 may also be elevated with the presence of other cancers. Preparation: No fasting required. Stop biotin consumption at least 72 hours prior to the collection. Test Results: 1-2 days.
Can stress cause tumor markers to rise?
The study, which followed 96 patients with chronic lymphocytic leukemia (CLL), found that those who felt more stress and anxiety about about their condition also had a higher volume of cancer cells in their blood and higher blood levels of markers for advanced disease.
What causes tumor markers to go up?
Tumor marker levels may be higher when there is cancer in the body. They are not very “specific,” meaning non-cancer health issues can also cause these levels to be higher. They must be used along with radiology tests and exams by your healthcare provider.
Can tumor markers be wrong?
There’s a chance that a tumor marker test can give a “false positive.” That means the results suggest a person has cancer or that the cancer is growing, even when it’s not. A tumor marker can also give a “false negative,” which means the results suggest a person doesn’t have cancer when they actually do.
What do tumor markers show?
A tumor marker is anything present in or produced by cancer cells or other cells of the body in response to cancer or certain benign (noncancerous) conditions that provides information about a cancer, such as how aggressive it is, what kind of treatment it may respond to, or whether it is responding to treatment.
What is the meaning of CA 19-9?
A substance released into the bloodstream by both cancer cells and normal cells. Too much CA 19-9 in the blood can be a sign of pancreatic cancer or other types of cancer or conditions.
Can pancreatitis elevate CA 19-9?
Serum CA 19-9 and alpha-fetoprotein levels in primary hepatocellular carcinoma and liver cirrhosis. Pancreatitis also causes elevated CA 19-9 levels, but such levels rarely exceed 100 to 120 units/ml.
Does CA 19-9 fluctuate?
The CA 19-9 level of the patient decreased from 120 U/mL pre-operation to 89 U/mL after resection. Upon receiving chemotherapy, his CA 19-9 level was fluctuating without significant clinical symptoms.