Quick Answer: Where does poorly differentiated thyroid cancer spread?

Where does thyroid cancer usually metastasize to?

Most patients with thyroid cancer have the cancer contained in the thyroid at the time of diagnosis. About 30% will have metastatic cancer, with most having spread of the cancer to the lymph nodes in the neck and only 1-4% having spread of the cancer outside of the neck to other organs such as the lungs and bone.

What is poorly differentiated papillary thyroid cancer?

Poorly differentiated thyroid carcinomas (PDTCs) are a rare subtype of thyroid carcinomas that are biologically situated between well-differentiated papillary/follicular thyroid carcinomas and anaplastic thyroid carcinomas (ATCs).

How do you know if thyroid cancer has spread?

Other symptoms of thyroid cancer that may be present early on before it has metastasized include: Changes in your voice or constant hoarseness. Pain or soreness in the front of the neck. A persistent cough.

Does poorly differentiated thyroid cancer produce thyroglobulin?

Poorly Differentiated Thyroid Cancers

The ability to concentrate iodine, express TSH receptor (TSH-R), and produce thyroglobulin is what distinguishes well-differentiated thyroid cancers from poorly differentiated or undifferentiated thyroid cancers.

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How long can you live with Stage 4 thyroid cancer?

Stage 4: In this stage, the tumor has spread into neck tissues under the skin, the trachea, esophagus, the larynx, or distant parts of the body such as the lungs or bones. The 10-year outlook significantly declines at this point: Only 21 percent of people diagnosed at this stage are alive after 10 years.

What happens to your body when you have thyroid cancer?

The most common locations for metastatic thyroid cancer are the lungs, liver and bones. If tumors develop in these (or other) parts of the body, complications such as pain, swelling and organ failure can occur.

Is poorly differentiated carcinoma curable?

It is now clear that some patients with poorly differentiated carcinoma of unknown primary site have extremely responsive neoplasms, and some are curable with combination chemotherapy.

What is well-differentiated thyroid cancer?

In cancer terminology, “well-differentiated” means the cancer cells resemble the normal cells from which they grew. Well-differentiated cancers grow more slowly and have a better prognosis than undifferentiated cancers, which are more aggressive and have poorer outcomes.

What is PDTC thyroid cancer?

Poorly differentiated thyroid carcinoma (PDTC) is a rare type of thyroid cancer accounting for < 6% of all thyroid malignancies [1]. Nevertheless, it is the second cause of death from follicular cell-derived thyroid cancer after anaplastic carcinoma [2]. Death is usually secondary to metastatic disease [3].

Do you feel sick with thyroid cancer?

Most often, thyroid cancer causes a lump and/or swelling of the neck, but it may also cause difficulty breathing or swallowing, as well as vocal hoarseness. Other symptoms include neck pain that may radiate up to your ears or a persistent cough not caused by illness.

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What is the life expectancy of someone with thyroid cancer?

Prognosis is the chance of recovery. The 5-year survival rate tells you what percent of people live at least 5 years after the cancer is found. Percent means how many out of 100. Overall, the 5-year survival rate for people with thyroid cancer is 98%.

What happens if thyroid cancer is left untreated?

If neglected, any thyroid cancer may result in symptoms because of compression and/or infiltration of the cancer mass into the surrounding tissues, and the cancer may metastasize to lung and bone.