What does it mean if a tumor is heterogeneous?


Why are tumors heterogeneous?

Phenotypic and functional heterogeneity arise among cancer cells within the same tumor as a consequence of genetic change, environmental differences, and reversible changes in cellular properties. Some cancers also contain a hierarchy in which tumorigenic cancer stem cells differentiate into non-tumorigenic progeny.

What does it mean if a mass is heterogeneous?

Heterogeneous refers to a structure with dissimilar components or elements, appearing irregular or variegated. For example, a dermoid cyst has heterogeneous attenuation on CT. It is the antonym for homogeneous, meaning a structure with similar components.

Can a heterogeneous mass be benign?

Soft tissue tumors are a heterogeneous group of benign and malignant lesions that develop from various nonepithelial, extraskeletal elements, including adipose tissue, smooth and skeletal muscle, tendon, cartilage, fibrous tissue, blood vessels, and lymphatic structures.

What does heterogeneous appearance mean?

Heterogeneous is a word pathologists use to describe tissue that looks very different from one area of the tissue to the next. Differences in colour, shape, and size can make a tissue look heterogeneous. Heterogeneous can be used to describe the way the tissue looks with or without a microscope.

What is a problem associated with tumor heterogeneity?

Tumor heterogeneity presents resistant clones that are not responsive to matching targeted therapy. Thus, targeting only one abnormality is not sufficient to be lethal for most, if not all, cancer cells [Engelman et al.

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What is called heterogeneous?

: consisting of dissimilar or diverse ingredients or constituents : mixed an ethnically heterogeneous population. Other Words from heterogeneous Synonyms & Antonyms More Example Sentences Learn More About heterogeneous.

Are cancers tumors?

What is the difference between a tumor and cancer? Cancer is a disease in which cells, almost anywhere in the body, begin to divide uncontrollably. A tumor is when this uncontrolled growth occurs in solid tissue such as an organ, muscle, or bone.

What is the example of heterogeneous?

A heterogeneous mixture is a mixture of two or more compounds. Examples are: mixtures of sand and water or sand and iron filings, a conglomerate rock, water and oil, a salad, trail mix, and concrete (not cement).

What does homogeneous mean in ultrasound?

Homogeneous: organ parenchyma is uniform in echogenicity (Figure 1-4). • Inhomogeneous or heterogeneous: organ parenchyma is not uniform in echogenicity (Figure 1-5).

What does homogeneous mass mean?

A mass that exhibits essentially the same physical properties at every point throughout the mass. Ref: ASCE.