Which chemotherapy causes mucositis?


Which chemotherapy drugs cause mucositis?

The chemotherapy drugs that have been reported to cause mucositis in 30% or more of patients are:

  • Actinomycin (Cosmegen)
  • Busulfan (Myleran®, Busulfex®)
  • Cytarabine (Cytosar-U®)
  • Daunorubicin (Cerubidine®)
  • Docetaxel (Taxotere®)
  • Doxorubicin (Adriamycin®, Rubex®)
  • Epirubicin (Ellence®)
  • Floxuridine (FUDR®)

Does doxorubicin cause mucositis?

Our study cohort included patients undergoing treatment based on either 5-FU or doxorubicin. Although both groups developed oral mucositis, its incidence was higher in the 5-FU group with a highly significant correlation seen between the total dose of 5-FU and the severity of lesions.

What is mucositis chemotherapy?

Mucositis is when your mouth or gut is sore and inflamed. It’s a common side effect of chemotherapy and radiotherapy for cancer. Although mucositis is usually painful, it can be treated. It should get better within a few weeks of finishing cancer treatment.

Which chemo drugs cause mouth sores?

The chemotherapy drugs most likely to cause mouth sores include:

  • Capecitabine (Xeloda)
  • Cisplatin.
  • Cytarabine (Depocyt)
  • Doxorubicin (Doxil)
  • Etoposide (Etopophos)
  • Fluorouracil.
  • Methotrexate (Trexall)

What is the fastest way to cure mucositis?

Actions that may help reduce the pain from mucositis: -In mild cases, ice pops, water ice, or ice chips may help numb the area, but most cases require more intervention for relief or pain. -Topical pain relievers include lidocaine, benzocaine, dyclonine hydrochloride (HCl), and Ulcerease® (0.6% Phenol).

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Is mucositis serious?

Oral mucositis is a clinically important and sometimes dose-limiting complication of cancer therapy. Mucositis lesions can be painful, affect nutrition and quality of life, and have a significant economic impact. The pathogenesis of oral mucositis is multifactorial and complex.

What does mucositis look like?

The signs and symptoms of mucositis can vary but can include: Red, shiny, or swollen mouth and gums. Blood in the mouth. Sores in the mouth, including on the gums or tongue.

How long does it take for mucositis to heal?

Healing usually takes 2 to 4 weeks. Mucositis caused by radiation therapy usually lasts 6 to 8 weeks, depending on how long you have radiation treatment.

What can I eat with mucositis?

What you can do: Improving your eating when you have mucositis

  • Try freezing fruits and suck on frozen fruit pops, fruit ice or ice chips.
  • Eat soft, creamy foods.
  • Blend and moisten foods that are dry or solid. …
  • Puree or liquefy foods in a blender to make them easier to swallow.

What is the treatment for mucositis?

Medications for Mucositis Treatment

Mouthwash containing a numbing agent to help numb the inside of your mouth. Topical anesthetics in gel or spray form to numb sore areas of your mouth. Benzydamine or corticosteroids to help with mouth pain. Mucosal protectants to coat your mouth lining and protect your nerve endings.

Who gets oral mucositis?

Mucositis is an inflammatory process that affects the mucous membranes of the oral cavity and gastrointestinal tract. ONS PEP resources focus on oral mucositis, which is estimated to occur in about 40% of patients secondary to chemotherapy and almost 100% of those receiving radiation for head and neck cancer.

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What do mouth sores from chemo look like?

Whitish, ulcer-like sores can form on your cheeks, gums, lips, tongue, or on the roof or floor of your mouth. Even if you don’t develop mouth ulcers, you may have patches that feel inflamed and painful, as if they’ve been burned.

What helps mouth sores from chemo naturally?

A toothpaste and mouth rinse containing essential oils is the best choice when trying to combat uncomfortable side effects from chemotherapy. Natural oral care products offer anti-inflammatory, antimicrobial, antibacterial and antifungal properties—all of which are advantageous during chemotherapy.

How do you prevent mouth sores from chemo?

The best way to manage mouth sores is to prevent them or treat them early. If you are receiving chemotherapy, sucking on ice chips right before and during treatment may prevent mouth sores. Visit a dentist that specializes in cancer care before starting radiation therapy to the head or neck area.