Can sebaceous carcinoma metastasis?


Does sebaceous carcinoma metastasize?

Sebaceous gland carcinoma (SGC) of the eyelid is an aggressive malignant eyelid tumor, and it can metastasize to the regional lymph nodes and distant organs.

Where does sebaceous carcinoma spread?

Sebaceous carcinoma is a rare skin cancer that forms in the sebaceous glands that lubricate the skin. While it can develop anywhere on the body, it is most commonly found on an eyelid. It can spread (metastasize) elsewhere in the body if untreated.

Is sebaceous carcinoma aggressive?

Sebaceous carcinoma is a rare and very aggressive malignant skin cancer of the sebaceous gland. While sebaceous glands are present all over the body, this malignancy is most commonly diagnosed in the head and neck: areas rich in sebaceous glands.

Does sebaceous carcinoma hurt?

SC tends to be painless. Without treatment, a stye can make blinking painful. The eyelid can swell, and the eyes may water. Most styes clear with treatment, which usually involves applying a warm compress 4 to 6 times a day.

Is sebaceous carcinoma hereditary?

Sebaceous carcinoma

It is considered to be a variant of hereditary nonpolyposis colorectal cancer syndrome (HNPCC). Cutaneous manifestations of Muir-Torre syndrome can occur before, concurrent with, or after the diagnosis of a visceral malignancy.

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What is Muir-Torre syndrome?

Muir-Torre syndrome (MTS) is a phenotypic variant of the hereditary nonpolyposis colorectal cancer (HNPCC) characterized by the association of sebaceous skin tumors and internal malignancies, most frequently colon cancer. It was first described by Muir et al1 in 1967 and then by Torre2 in 1968.

How quickly does sebaceous carcinoma grow?

In general, extraocular sebaceous carcinoma is less aggressive than ocular sebaceous carcinoma [4]. However, some authors have reported that extraocular tumors preferentially show a rapid growth. This is especially true in elderly women [6]. In the present patient, the lesion was rapidly growing in just 2 weeks.

Can sebaceous carcinoma spread?

Sebaceous carcinoma can spread to other areas of the body and may be difficult to treat.

How is sebaceous carcinoma treated?

Sebaceous Carcinoma Treatments

Excision or surgical removal of the tumor and some surrounding tissue. Cryotherapy, which freezes the growth with liquid nitrogen. Surgery to remove lymph nodes, if the cancer has spread. Radiation, if the cancer has spread or if surgery is not an option.

How common is sebaceous cell carcinoma?

It represents 1–5.5% of eyelid malignancies and is considered to be the third most common eyelid malignancy after basal cell and squamous cell carcinomas, although few reports placed this tumor as second most common after basal cell carcinoma.

What causes sebaceous cell carcinoma?

The exact cause of sebaceous carcinoma is unclear. The following have been reported to possibly increase the risk of these tumours: Underlying Muir-Torre or Lynch syndrome. Previous radiation therapy to the area for a variety of benign and malignant conditions, such as retinoblastoma.

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What is adenoma carcinoma?

Listen to pronunciation. (A-deh-noh-KAR-sih-NOH-muh) Cancer that begins in glandular (secretory) cells. Glandular cells are found in tissue that lines certain internal organs and makes and releases substances in the body, such as mucus, digestive juices, or other fluids.