How effective is tamoxifen in treating breast cancer?
Tamoxifen can: reduce the risk of breast cancer coming back by 40% to 50% in postmenopausal women and by 30% to 50% in premenopausal women. reduce the risk of a new cancer developing in the other breast by about 50% shrink large, hormone-receptor-positive breast cancers before surgery.
What is the success rate of tamoxifen?
The study found that patients with 5 years of tamoxifen treatment showed better disease free survival than patients with 10 years of treatment (82% vs 78%, P = . 03), and no statistically significant differences in survival rate were found between these 2 groups (94% vs 91%, P = . 07).
Can you still get breast cancer if taking tamoxifen?
Cancers linked to treatment with tamoxifen
Taking tamoxifen lowers the chance of hormone receptor-positive breast cancer coming back. It also lowers the risk of a second breast cancer. Tamoxifen does, however, increase the risk for uterine cancer (endometrial cancer and uterine sarcoma).
Does tamoxifen keep cancer away?
“In general, tamoxifen for five years reduces the probability of breast cancer recurrence by almost 50 percent, while risks of serious side effects are at around 1 percent or less,” he explained.
What are the worst side effects of tamoxifen?
You should call your healthcare provider if you’re taking tamoxifen and experience:
- Chest pain or shortness of breath.
- Signs of stroke, including slurred speech, blurred vision or sudden numbness in the legs, arms or face.
- Swelling in the legs, ankles or feet.
- Uncontrolled vomiting.
Is tamoxifen a type of chemo?
Tamoxifen – Chemotherapy Drugs – Chemocare.
Is tamoxifen toxic to the liver?
Tamoxifen is a nonsteroidal antiestrogen that is widely used in the treatment and prevention of breast cancer. Long term tamoxifen therapy has been associated with development of fatty liver, steatohepatitis, cirrhosis, and rare instances of clinically apparent acute liver injury.
Why you should not take tamoxifen?
Tamoxifen may cause hot flashes and increase the risk of blood clots and stroke. Aromatase inhibitors may cause muscle and joint aches and pains. Less common but more severe side effects of aromatase inhibitors are heart problems, osteoporosis, and broken bones.
Does tamoxifen affect memory?
The researchers found that tamoxifen users had lower scores in verbal memory and executive functioning — which includes such things as being able to shift attention between two different parts of a task — than did women without breast cancer.
Can you live 20 years after breast cancer?
Since the hazard rate associated with inflammatory breast cancer shows a sharp peak within the first 2 years and a rapid reduction in risk in subsequent years, it is highly likely that the great majority of patients alive 20 years after diagnosis are cured.
What foods should not be eaten when taking tamoxifen?
The foods of most concern for women taking tamoxifen are grapefruit and tangerines. Grapefruit is well-known to interfere with numerous medications. Many drug-interaction resources specifically advise that women taking tamoxifen avoid grapefruit.
Can tamoxifen affect your eyes?
The usual daily dose of tamoxifen is 20-40 mgs. Ocular side effects are relatively uncommon and are usually associated with higher doses. The ocular side effects are blurred vision, decreased visual acuity, vortex keratopathy, retinotoxicity, and bilateral optic neuritis.