Can a heterogeneous mass be benign?
Soft tissue tumors are a heterogeneous group of benign and malignant lesions that develop from various nonepithelial, extraskeletal elements, including adipose tissue, smooth and skeletal muscle, tendon, cartilage, fibrous tissue, blood vessels, and lymphatic structures.
Are malignant tumors heterogeneous or homogeneous?
Clonal heterogeneity within primary tumors is only one of the aspects of clonal heterogeneity of cancers. Cancer is a systemic disease: malignant cancers shed large numbers of cells into the blood stream and lymph vessels; some of these cells settle down in distant sites and develop into metastases.
Can you tell if a mass is cancerous without a biopsy?
Normal cells will look uniform, and cancer cells will appear disorganized and irregular. Most of the time, a biopsy is needed to know for sure if you have cancer. It’s considered the only definitive way to make a diagnosis for most cancers.
What does heterogeneous appearance mean?
Heterogeneous refers to a structure with dissimilar components or elements, appearing irregular or variegated.
Why are cancer cells heterogeneous?
Phenotypic and functional heterogeneity arise among cancer cells within the same tumor as a consequence of genetic change, environmental differences, and reversible changes in cellular properties. Some cancers also contain a hierarchy in which tumorigenic cancer stem cells differentiate into non-tumorigenic progeny.
What is a heterogeneous condition?
A heterogeneous medical condition or heterogeneous disease is a medical term referring to a medical condition with several etiologies (root causes), such as hepatitis or diabetes.
Does a mass mean cancer?
In medicine, a lump in the body. It may be caused by the abnormal growth of cells, a cyst, hormonal changes, or an immune reaction. A mass may be benign (not cancer) or malignant (cancer).
What causes tumor heterogeneity?
To a substantial extent, this heterogeneity might be attributed to morphological and epigenetic plasticity, but there is also strong evidence for the co-existence of genetically divergent tumor cell clones within tumors.
What is a problem associated with tumor heterogeneity?
Tumor heterogeneity presents resistant clones that are not responsive to matching targeted therapy. Thus, targeting only one abnormality is not sufficient to be lethal for most, if not all, cancer cells [Engelman et al.
What is the example of heterogeneous?
A heterogeneous mixture is a mixture of two or more compounds. Examples are: mixtures of sand and water or sand and iron filings, a conglomerate rock, water and oil, a salad, trail mix, and concrete (not cement).
Is blood homogeneous or heterogeneous?
Blood is heterogenous as the blood cells are physically seperated from the plasma.