What kind of treatment will I need?
What genes are affected by bladder cancer?
Somatic mutations in the FGFR3, PIK3CA, KDM6A, and TP53 genes are common in bladder cancers. Each of these genes plays a critical role in regulating gene activity and cell growth, ensuring cells do not grow and divide too rapidly or uncontrollably.
What are the 3 types of bladder cancer?
The 3 main types of bladder cancer are:
- Urothelial carcinoma. Urothelial carcinoma (or UCC) accounts for about 90% of all bladder cancers. …
- Squamous cell carcinoma. Squamous cells develop in the bladder lining in response to irritation and inflammation. …
What are the signs that bladder cancer has spread?
The signs and symptoms of bladder cancer that has spread to other parts of the body include:
- tiredness or weakness.
- pain when urinating.
- difficulty urinating or inability to urinate.
- pain in the lower back on one side of the body.
- weight loss.
- swollen feet.
- bone pain.
Is there pain with bladder cancer?
When it’s in its earliest stages, bladder cancer doesn’t usually cause much pain. Some people have no pain whatsoever, while others may experience pain or burning when they urinate. Blood in the urine, either microscopic or visible to the naked eye, is commonly the first sign of bladder cancer.
What are the symptoms of advanced bladder cancer?
Symptoms of Advanced Bladder Cancer
- An inability to urinate.
- Lower back pain on one side of the body.
- Loss of appetite.
- Unintended weight loss.
- Overwhelming fatigue.
- Bone pain.
- Swelling in the feet.
Do you feel ill with bladder cancer?
Feeling weak or fatigued: You may feel lethargic and extremely tired a lot of the time. Bone pain: If your cancer has spread to the bone, it can cause bone pain or a bone fracture.
Is bladder cancer curable if caught early?
Bladder cancer is usually treatable when caught at an early stage but more challenging to address when found later. Recurrence also poses a risk, even with early-stage tumors, so regular surveillance is essential following treatment or surgery.
What is the life expectancy for someone with bladder cancer?
The general 5-year survival rate for people with bladder cancer is 77%. However, survival rates depend on many factors, including the type and stage of bladder cancer that is diagnosed. The 5-year survival rate of people with bladder cancer that has not spread beyond the inner layer of the bladder wall is 96%.
Where does bladder cancer spread first?
Local bladder cancer metastasis
When bladder cancer spreads, it first invades the bladder wall, which is made up of four distinct layers. It can take some time for cancer to penetrate all of these layers, but once it has, it can then spread into the surrounding fatty tissues and lymph nodes.
Can you have bladder cancer for years and not know it?
Even after reporting the problem to their doctors, blood in the urine may be initially misdiagnosed. It may be seen as a symptom of post-menopausal bleeding, simple cystitis or as a urinary tract infection. As a result, a bladder cancer diagnosis can be overlooked for a year or more.