How does disruption of the cell cycle and it’s checkpoints result in cancer?

How do cell cycle checkpoints relate to cancer?

Two checkpoints are sensitive to DNA damage, one that acts before mitosis and a second that acts before DNA replication. This is relevant to cancer because checkpoint mutants show genetic instability, and such instability is characteristic of many cancers.

What would happen if there is a disruption to the cell cycle?

Disruption of normal regulation of the cell cycle can lead to diseases such as cancer. When the cell cycle proceeds without control, cells can divide without order and accumulate genetic errors that can lead to a cancerous tumor .

What part of the cell cycle is most affected by cancer?

All dividing cells must go through the process of DNA replication. Since cancer cells are often rapidly dividing, this phase of the cell cycle is the target of many of the chemotherapy.

What occurs if a cell is damaged beyond repair?

Explanation: Apoptosis is programmed cell death, and it usually occurs when the DNA of the cell is damaged beyond repair.

THIS IS IMPORTANT:  Can Black get skin cancer?