How long should you take tamoxifen after breast cancer?
Most people take tamoxifen or other hormone therapy for at least five years and sometimes up to 10 years. Treatment length depends on the features of your cancer diagnosis. Your healthcare provider may recommend taking tamoxifen for five years and then switching to different hormone therapy for several more years.
What happens when I stop taking tamoxifen?
Blood clots in your veins or lungs.
These can occur for up to 2–3 months after you stop taking tamoxifen. Symptoms can include: sudden chest pain.
Is 5 years of tamoxifen enough?
Currently, tamoxifen is usually given daily for five years after a cancer is treated. Doctors have known that five years is more effective than two, and that it reduces the rate of death from breast cancer by about a third in comparison to not taking it, and that it does so for 15 years after the diagnosis.
How long can you take tamoxifen safely?
A recent study published in the British Journal of Medicine indicated clear evidence that 10 years of tamoxifen therapy does reduce local recurrence and improve breast cancer-free survival. However, it also reported that extended use (10 years rather than five) was linked with a two-fold increase in endometrial cancer.
Does breast cancer come back when on tamoxifen?
Doctors have long known that five years of tamoxifen reduces recurrence by about half during treatment and by nearly a third over the next five years. Aromatase inhibitors, which work only in postmenopausal women, are even more effective than tamoxifen at reducing recurrence and death from breast cancer.
Can I drink green tea while taking tamoxifen?
The combination of tamoxifen with green tea catechins could enhance its action in ER-negative breast cancer. In addition, such a combination could allow a dosage reduction of breast endocrine treatment in ER-positive breast cancer and in breast cancer chemoprophylaxis, leading to an amelioration of the safety profile.
What are the long term effects of tamoxifen?
Tamoxifen can have side effects, including hot flashes, fatigue, and an increased risk of blood clots and endometrial cancer. But there was no substantial increase in serious side effects, including endometrial cancer incidence or death, in women who took tamoxifen for the longer period, Gray reported.
What foods should not be eaten when taking tamoxifen?
The foods of most concern for women taking tamoxifen are grapefruit and tangerines. Grapefruit is well-known to interfere with numerous medications. Many drug-interaction resources specifically advise that women taking tamoxifen avoid grapefruit.
Do tamoxifen side effects get worse over time?
A German study suggests that women who expect to have more and more severe side effects before hormonal therapy starts do have worse side effects after 2 years of treatment.
What is the success rate of tamoxifen?
The study found that patients with 5 years of tamoxifen treatment showed better disease free survival than patients with 10 years of treatment (82% vs 78%, P = . 03), and no statistically significant differences in survival rate were found between these 2 groups (94% vs 91%, P = . 07).
Why you should not take tamoxifen?
Tamoxifen may cause hot flashes and increase the risk of blood clots and stroke. Aromatase inhibitors may cause muscle and joint aches and pains. Less common but more severe side effects of aromatase inhibitors are heart problems, osteoporosis, and broken bones.
What is the best time to take tamoxifen?
Tamoxifen may be taken at any time of the day but should be taken at the same time each day. it is within 12 hours of the missed dose.