What is the normal range for breast cancer tumor markers?

What is a good tumor marker number?

Normal range: < 2.5 ng/ml. Normal range may vary somewhat depending on the brand of assay used. Levels > 10 ng/ml suggest extensive disease and levels > 20 ng/ml suggest metastatic disease.

Are tumor markers accurate for breast cancer?

There has been no evidence to prove that tumor markers are 100 percent reliable for determining the presence or absence of cancer. Many circumstances, such as other health issues or disease, can contribute to raised tumor marker levels.

How high can breast cancer tumor markers go?

Cancer antigen 27-29 (CA 27-29) is used to predict early recurrence of disease in women with treated carcinoma of the breast. The reference range of serum CA 27-29 is less than 38 U/mL. The upper limit of the range may vary depending on the laboratory and testing kit used for the test.

What is a high CEA level for breast cancer?

Levels of CEA higher than 20 ng/mL are considered very high. If you have CEA levels this high and you also have symptoms of cancer, it strongly suggests the cancer has not been removed successfully after treatment. It may also suggest that the cancer has metastasized, or spread, to other parts of your body.

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What is a bad CA 125 level?

The tumor marker Ca 125 is a prognostic factor. Levels around 100 U/l are indicative of a bad prognosis.

Can stress cause tumor markers to rise?

The study, which followed 96 patients with chronic lymphocytic leukemia (CLL), found that those who felt more stress and anxiety about about their condition also had a higher volume of cancer cells in their blood and higher blood levels of markers for advanced disease.

Which tumor marker is used to determine the stage of breast cancer?

In breast cancer care, three tumor markers — cancer antigen 15-3 (CA 15-3), cancer antigen 27.29 (CA 27.29), and carcinoembryonic antigen (CEA) — have been used to help monitor metastatic breast cancer (advanced disease), but they have not been found to be useful to find a breast cancer recurrence or lengthen lives …

Can breast cancer raise CA125 levels?

In our study, patients with late-stage breast cancer exhibited significantly higher levels of CEA, CA125 and CA15-3 compared with early-stage ones, suggesting that the serum levels of these tumor markers might be more efficient for monitoring advanced tumors than early diagnosis.

Will breast cancer show up in blood work?

Breast cancer could be detected up to five years before there are any clinical signs of it, using a blood test that identifies the body’s immune response to substances produced by tumor cells, according to new research.

What is a good CA 125 level?

The normal value is less than 46 U/mL. If your CA 125 level is higher than normal, you may have a benign condition, or the test result could mean that you have ovarian, endometrial, peritoneal or fallopian tube cancer. Your doctor may recommend other tests and procedures to determine your diagnosis.

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How accurate is tumor marker CA 15-3?

CA 15-3 in the diagnostic and follow up of patients with breast cancer has a sensitivity ranging from 75-76.9% and the specificity ranging from 85.5-93%.

What is a normal CEA tumor marker?

Tumor marker, CEA: Carcinoembryonic antigen (CEA) is a protein found in many types of cells but associated with tumors and the developing fetus. CEA is tested in blood. The normal range is <2.5 ng/ml in an adult non-smoker and <5.0 ng/ml in a smoker.

What is CEA test for breast cancer?

CEA (carcinoembryonic antigen): a marker for the presence of colon, lung, and liver cancers. This marker may be used to determine if the breast cancer has traveled to other areas of the body. Circulating tumor cells: cells that break off from the cancer and move into the blood stream.

What causes CEA to rise?

The most frequent cancer which causes an increased CEA is cancer of the colon and rectum. Benign conditions which can elevate CEA include smoking, infections, inflammatory bowel disease, pancreatitis, cirrhosis of the liver, and some benign tumors in the same organs in which an elevated CEA level indicates cancer.