Can Hurthle cell adenoma become malignant?
These cells are often benign, but they can be malignant and metastasize. Hürthle cells are resistant to radiation, but can be treated using radioactive iodine treatment.
Are follicular cells cancerous?
Follicular thyroid carcinoma (FTC) is the second most common cancer of the thyroid, after papillary carcinoma. Follicular and papillary thyroid cancers are considered to be differentiated thyroid cancers; together they make up 95% of thyroid cancer cases.
How common is Hurthle cell adenoma?
Hurthle cell carcinoma (HCC) represents approximately 5% of differentiated thyroid carcinomas 1. Hurthle cell tumour (HCT) is a rare thyroid neoplasm of follicular cell origin, > 75% being composed of cells with oncocytic features.
Are neoplasms always malignant?
Neoplasms may be benign (not cancer) or malignant (cancer). Benign neoplasms may grow large but do not spread into, or invade, nearby tissues or other parts of the body. Malignant neoplasms can spread into, or invade, nearby tissues.
What is neoplasm disease?
Neoplastic diseases are conditions that cause tumor growth — both benign and malignant. Benign tumors are noncancerous growths. They usually grow slowly and can’t spread to other tissues. Malignant tumors are cancerous and can grow slowly or quickly.
Are Hürthle cells normal?
Follicular and hurthle cells are normal cells found in the thyroid. Current analysis of thyroid biopsy results cannot differentiate between follicular or hurthle cell cancer from noncancerous adenomas. This occurs in 15-20% of biopsies and often results in the need for surgery to remove the nodule.
What percentage of thyroid follicular neoplasms are benign?
The diagnosis “follicular neoplasm” is indeterminate, and the majority of cases (70% in the current study) are benign. However, clinical features, including gender, nodule size, and age, can be a part of the decision analysis in selecting patients for surgery.
What is the treatment of follicular neoplasm?
The preferred treatment for follicular neoplasms is lobectomy followed by completion total thyroidectomy for histologically proven carcinomas larger than 1.0 cm. Total thyroidectomy allows use of thyroglobulin and radioiodine scanning to detect and treat metastatic disease.
Is follicular neoplasm curable?
The diagnosis of follicular thyroid cancers that are less than 1.5 cm in size (less than ½ inch) have the best cure rates (nearly 100% for small follicular thyroid cancers in young patients).