Which is used to treat breast cancer that is HER2 positive and has spread after treatment with other drugs?

What medication is used for HER2-positive breast cancer?

Pertuzumab (Perjeta) treats HER2-positive early breast cancer, usually in combination with trastuzumab and chemotherapy. It’s FDA-approved for neoadjuvant and adjuvant treatment.

Is Herceptin immunotherapy or chemotherapy?

Herceptin is an intravenous drug that is part of a chemotherapy regimen that is used to prevent recurrence of breast cancer, and for the treatment breast cancer that has spread beyond the breast (metastasized). It belongs to a class of drugs called monoclonal antibodies.

What are HER2 inhibitors used to treat?

Anti-HER2 therapies (also called HER2 inhibitors or HER2-targeted therapies) are a class of medicines used to treat all stages of HER2-positive breast cancer, from early-stage to metastatic. Metastatic breast cancer is cancer that has spread to other parts of the body away from the breast, such as the bones or liver.

What is Herceptin used for?

Herceptin is the brand name of a medicine called trastuzumab. It’s used to treat some types of breast cancer, oesophageal cancer and stomach cancer.

Is HER2-positive a death sentence?

Current treatment algorithms for invasive HER2-positive disease has transformed the face of a disease with a death sentence to one with prolonged and overall survival benefit.

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What is the success rate of Herceptin?

At 10 years after treatment, overall survival was better in women who were treated with Herceptin: 84% of the women who received chemotherapy plus Herceptin were alive. 75.2% of the women who received chemotherapy alone were alive.

How does Herceptin make you feel?

The most common adverse reactions in patients receiving Herceptin in the adjuvant and metastatic breast cancer setting are fever, nausea, vomiting, infusion reactions, diarrhea, infections, increased cough, headache, fatigue, dyspnea, rash, neutropenia, anemia, and myalgia.

Why is Herceptin given for a year?

Since 2005, the standard of care has been to give Herceptin for 1 year after surgery and chemotherapy to reduce the risk of recurrence (the cancer coming back) of early-stage, HER2-positive breast cancer. Like most cancer treatments, Herceptin can cause side effects, including possible heart damage.

Is it better to be HER2-positive or negative?

Is HER2-positive breast cancer good or bad? HER2-positive cancer tends to be poorer in terms of prognosis than HER2-negative cancer because: It grows faster. It is more likely to spread to the lymph nodes fast.

Is chemo necessary for HER2-positive?

Trastuzumab and chemotherapy are even recommended for women with very small, HER2-positive breast cancers. Tumors as small as 0.5 cm often warrant such treatment. However, decisions must be individualized based on your own individual risk.

Is chemo necessary for HER2-negative?

Hormonal therapy is considered the standard initial treatment for HER2-negative metastatic breast cancer that is also hormone receptor-positive, and is often given in combination with targeted therapy. However, chemotherapy may also be given. A clinical trial may also be an option for treatment at any stage.

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How long can you stay on Herceptin?

Official Answer. When Perjeta (generic name: pertuzumab) and Herceptin (generic name: trastuzumab) are used to treat HER2+ early breast cancer as adjuvant treatment (after surgery), this regimen may be continued every 3 weeks for one year (up to 18 cycles).

Will my hair grow back while on Herceptin?

Your hair may thin but you’re unlikely to lose all your hair. This usually starts after your first or second cycle of treatment. It is almost always temporary and your hair will grow back when you finish your treatment.