How quickly does choriocarcinoma spread?
Choriocarcinoma can develop some months or even years after pregnancy and can be difficult to diagnose, because it is so unexpected. They can grow quickly and might cause symptoms within a short period of time. They can spread to other parts of the body but are very likely to be cured by chemotherapy treatment.
Can choriocarcinoma cancer be cured?
Most women whose cancer has not spread can be cured and will still be able to have children. A choriocarcinoma may come back within a few months to 3 years after treatment. The condition is harder to cure if the cancer has spread and one or more of the following happens: Disease spreads to the liver or brain.
How is choriocarcinoma treated?
Treatment of low-risk gestational trophoblastic neoplasia (GTN) (invasive mole or choriocarcinoma) may include the following: Chemotherapy with one or more anticancer drugs. Treatment is given until the beta human chorionic gonadotropin (β-hCG) level is normal for at least 3 weeks after treatment ends.
Can Stage 4 choriocarcinoma be cured?
Fortunately, most women who are found to have choriocarcinoma can be cured; treatment with a combination of chemotherapy agents such as etoposide, methotrexate, actinomycin D, cyclophosphamide and vincristine (EMA-CO) is found to be very effective at achieving remission.
How is choriocarcinoma detected?
If your doctor thinks you have choriocarcinoma, they’ll do some tests:
- A pelvic exam to feel for lumps or unusual changes.
- A test to look for levels of a hormone called hCG. …
- Blood and urine tests.
- An exam to see if the cancer has spread to other parts of your body.
- Imaging tests such as CT, MRI, ultrasound, or X-ray.
What are the signs and symptoms of choriocarcinoma?
Symptoms of choriocarcinoma which has spread
- lungs – you might have a cough, difficulty breathing and sometimes chest pain.
- vagina – you might have heavy bleeding, and your doctor might be able to feel a lump (nodules) in your vagina.
- abdomen – you might have abdominal pain.
Where can choriocarcinoma spread?
Although choriocarcinoma starts in the womb, it can spread to other parts of the body – most commonly, the lungs. If it spreads to your lungs, you may have symptoms such as coughing, difficulty breathing and chest pain.
How curable is cancer of the uterus?
While a diagnosis of uterine cancer can be scary, it is important to know that its most common form—endometrial cancer—is highly curable. Uterine cancer is a blanket term for a group of cancers that can develop inside a woman’s uterus.
Can choriocarcinoma be seen on ultrasound?
An ultrasound scan can diagnose many women with persistent trophoblastic disease or choriocarcinoma.
Is choriocarcinoma genetic?
Choriocarcinoma is of gestational origin if a paternal component can be identified by DNA analysis or HLA typing [7–10]. Molecular genetic diagnosis, for example, fluorescent microsatellite genotyping, can therefore be used to evaluate the genetic origin of hCG-producing tumors with trophoblastic differentiation.
Can men develop choriocarcinoma?
Choriocarcinoma predominantly occurs in women but can also occur in men, usually as part of a mixed germ cell tumor. This activity reviews the clinical evaluation of choriocarcinoma and the role of the interprofessional team in caring for patients with this disease.