Can sebaceous carcinoma spread?


Where does sebaceous carcinoma spread?

Sebaceous carcinoma is a rare skin cancer that forms in the sebaceous glands that lubricate the skin. While it can develop anywhere on the body, it is most commonly found on an eyelid. It can spread (metastasize) elsewhere in the body if untreated.

Does sebaceous carcinoma metastasize?

Sebaceous gland carcinoma (SGC) of the eyelid is an aggressive malignant eyelid tumor, and it can metastasize to the regional lymph nodes and distant organs.

Is sebaceous carcinoma fatal?

Sebaceous carcinoma can develop in any sebaceous glands, which lubricate the skin, but it most often begins on or around the eyelids. If it is found and treated early, treatment is often successful. However, if sebaceous carcinoma spreads, it can be deadly.

How quickly does sebaceous carcinoma grow?

In general, extraocular sebaceous carcinoma is less aggressive than ocular sebaceous carcinoma [4]. However, some authors have reported that extraocular tumors preferentially show a rapid growth. This is especially true in elderly women [6]. In the present patient, the lesion was rapidly growing in just 2 weeks.

How is sebaceous carcinoma treated?

Treatment. Sebaceous carcinoma treatment typically involves surgery to remove the cancer. Radiation therapy and experimental treatments may be options if you can’t undergo surgery.

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Is sebaceous carcinoma painful?

SC tends to be painless. Without treatment, a stye can make blinking painful. The eyelid can swell, and the eyes may water.

Is sebaceous carcinoma hereditary?

Sebaceous carcinoma

It is considered to be a variant of hereditary nonpolyposis colorectal cancer syndrome (HNPCC). Cutaneous manifestations of Muir-Torre syndrome can occur before, concurrent with, or after the diagnosis of a visceral malignancy.

What is Muir-Torre syndrome?

Muir-Torre syndrome (MTS) is a phenotypic variant of the hereditary nonpolyposis colorectal cancer (HNPCC) characterized by the association of sebaceous skin tumors and internal malignancies, most frequently colon cancer. It was first described by Muir et al1 in 1967 and then by Torre2 in 1968.

What is atypical sebaceous neoplasm?

Peri-ocular sebaceous carcinomas are composed of enlarged atypical epithelioid cells usually with basaloid features and hyperchromatic nuclei (Fig. 7D). The degree of cytological atypia is significantly greater than that encountered in sebaceous adenoma or sebaceoma, but is not always prominent.

How common is sebaceous cell carcinoma?

It represents 1–5.5% of eyelid malignancies and is considered to be the third most common eyelid malignancy after basal cell and squamous cell carcinomas, although few reports placed this tumor as second most common after basal cell carcinoma.

How do you know if a sebaceous cyst is cancerous?

A sebaceous cyst is possibly cancerous if it has any of these characteristics: A sign of infection such as pain, redness or pus drainage. A fast rate of growth after being removed. A diameter that’s larger than five centimeters.

What are the signs and symptoms of sebaceous gland carcinoma?

Sebaceous carcinoma: Signs and symptoms

  • Slowly growing, often yellowish lump on the eyelid that feels firm, deep, and painless.
  • Thickening of an eyelid, where lid meets lash.
  • Yellow or reddish crust on eyelid, where lid meets lash.
  • Growth on eyelid that looks like a pimple.
  • Growth on eyelid that bleeds.
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