Where does bladder cancer most commonly metastasize to?
Conclusion: Lymph nodes, bones, lung, liver, and peritoneum are the most common sites of metastasis from bladder cancer. Tumors in a more advanced T category and those with atypical histologic features metastasize earlier.
Where is the first place bladder cancer spreads?
When bladder cancer spreads, it first invades the bladder wall, which is made up of four distinct layers. It can take some time for cancer to penetrate all of these layers, but once it has, it can then spread into the surrounding fatty tissues and lymph nodes.
How long does it take bladder cancer to metastasize?
As many as 50% of patients with muscle-invasive bladder cancer may have occult metastases that become clinically apparent within 5 years of initial diagnosis and around 5% will have distant metastasis at the time of initial diagnosis. Most patients with overt metastatic disease die within 2 years despite chemotherapy.
What are the signs that bladder cancer has spread?
The signs and symptoms of bladder cancer that has spread to other parts of the body include:
- tiredness or weakness.
- pain when urinating.
- difficulty urinating or inability to urinate.
- pain in the lower back on one side of the body.
- weight loss.
- swollen feet.
- bone pain.
Is there pain with bladder cancer?
When it’s in its earliest stages, bladder cancer doesn’t usually cause much pain. Some people have no pain whatsoever, while others may experience pain or burning when they urinate. Blood in the urine, either microscopic or visible to the naked eye, is commonly the first sign of bladder cancer.
How long will you live if you have bladder cancer?
The general 5-year survival rate for people with bladder cancer is 77%. However, survival rates depend on many factors, including the type and stage of bladder cancer that is diagnosed. The 5-year survival rate of people with bladder cancer that has not spread beyond the inner layer of the bladder wall is 96%.
Do you feel ill with bladder cancer?
Feeling weak or fatigued: You may feel lethargic and extremely tired a lot of the time. Bone pain: If your cancer has spread to the bone, it can cause bone pain or a bone fracture.
Can you have bladder cancer for years and not know it?
Even after reporting the problem to their doctors, blood in the urine may be initially misdiagnosed. It may be seen as a symptom of post-menopausal bleeding, simple cystitis or as a urinary tract infection. As a result, a bladder cancer diagnosis can be overlooked for a year or more.
What are the symptoms of late stage bladder cancer?
What can I expect if I have stage 4 bladder cancer?
- blood or blood clots in your urine.
- pain or burning during urination.
- frequent urination.
- needing to urinate at night.
- needing to urinate but not being able to.
- lower back pain on one side of the body.
What happens in the final stages of bladder cancer?
Decreased amount of urine. Loss of bladder and bowel control. Restlessness or repetitive, involuntary movements. Confusion about time, place, and identity of people, including family members and close friends.
What is the most aggressive type of bladder cancer?
Muscle invasive bladder cancer is a serious and more advanced stage of bladder cancer. MIBC is when the cancer has grown far into the wall of the bladder (Stages T2 and beyond). For patients with MIBC, the overall prognosis (how the disease may progress) is dependent on stage and treatment.
How long can you live with metastatic kidney cancer?
In the case of kidney cancer, around 72% of those diagnosed live for at least one year after diagnosis, about 56% live for at least 5 years and about 50% live for 10 years or more.
How do you know if kidney cancer has spread to the bones?
When it does occur, signs and symptoms of bone metastasis include:
- Bone pain.
- Broken bones.
- Urinary incontinence.
- Bowel incontinence.
- Weakness in the legs or arms.
- High levels of calcium in the blood (hypercalcemia), which can cause nausea, vomiting, constipation and confusion.
How long can you live with Stage 4 metastatic kidney cancer?
Stage 4 metastatic patients have a five-year survival rate of just 10 percent. It’s not a death sentence, but it’s close. As recently as 15 years ago, there was just one drug approved by the Food and Drug Administration to treat stage 4 kidney cancer.