What does it mean when a cancer cell is undifferentiated?

Is undifferentiated cancer bad?

Tumours that are undifferentiated or poorly differentiated tend to be more aggressive. They tend to grow more quickly, spread more often and have a worse prognosis than tumours with well-differentiated cancer cells. Cancers that are undifferentiated or poorly differentiated are high grade.

Are cancer cells differentiated or undifferentiated?

Well-differentiated cancer cells look more like normal cells and tend to grow and spread more slowly than poorly differentiated or undifferentiated cancer cells. Differentiation is used in tumor grading systems, which are different for each type of cancer.

How is undifferentiated carcinoma treated?

Currently, it is believed that the best treatment for sinonasal undifferentiated carcinoma consists of multiple therapies, including surgery to remove as much of the tumor as possible, and chemotherapy and/or radiation therapy to destroy any cancer cells that may remain in the body.

What does highly undifferentiated mean?

: not divided or able to be divided into different elements, types, etc. : not differentiated undifferentiated cells an undifferentiated mass.

What stage of cancer is poorly differentiated?

High grade or grade III tumor cells are poorly differentiated. This means that the tumor cells don’t look like normal cells. They’re disorganized under the microscope and tend to grow and spread faster than grade I tumors.

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Is poorly differentiated carcinoma curable?

It is now clear that some patients with poorly differentiated carcinoma of unknown primary site have extremely responsive neoplasms, and some are curable with combination chemotherapy.

What does undifferentiated mean in medical terms?

A term used to describe cells or tissues that do not have specialized (“mature”) structures or functions. Undifferentiated cancer cells often grow and spread quickly.

What causes sinonasal carcinoma?

Smoking and exposure to heavy metals, such as nickel, also increase the risk for developing sinus tumors. Symptoms of sinus cancer may include a mass in the neck beneath the skin, numbness on the side of the nose, one-sided nosebleeds, nasal congestion and a persistent lump or sore inside the nose.

What is undifferentiated sarcoma?

A group of rare cancers that do not look like other types of sarcomas under a microscope and may be hard to diagnose. They usually form in the muscles that are attached to bones and that help the body move. Undifferentiated sarcomas tend to grow quickly and spread to other parts of the body.

What is undifferentiated nasopharyngeal carcinoma?

Abstract. Undifferentiated carcinoma of the nasopharynx (UCNT) is a particular head and neck epidermoid lineage tumor related to the Epstein Barr Virus (EBV). It has geographically selective endemic epidemiologic features, without relation to external carcinogens.

What does the word differentiated versus undifferentiated mean?

Moderately differentiated – These tumour cells are abnormal looking but still share some features with normal, healthy cells. Poorly differentiated – These tumours cells look very little like normal, healthy cells. Undifferentiated – These tumour cells look and behave nothing like normal, healthy cells.

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What is the difference between differentiated and undifferentiated marketing?

Differentiated marketing focuses on a specific market, a “different” market, that is interested in buying a certain type of product. … On the other hand, undifferentiated marketing is designed to appeal to a broad range of customers.

What stage is undifferentiated carcinoma?

The definitions of undifferentiated carcinoma and grade 3 endometrioid adenocarcinoma that we use in this study are the following: undifferentiated carcinoma is a malignant epithelial tumor composed of medium-sized cells with a complete absence of glandular differentiation and with absent or minimal neuroendocrine …